THERMAL IMAGING STUDY OF HUMAN SOFT TISSUE LESIONS AND BIOLOGICAL TISSUE EXPOSURE TO LOW-TEMPERATURE in vivo
Keywords:thermography, soft tissues, burns, frostbite, low temperature exposure
Introduction. Infrared thermography has been currently used in clinical practice only as an additional method
because of insufficient knowledge of the pathophysiological basis of thermal images.
Problem Statement. The main method for diagnosing the severity of soft tissue wound is a visual assessment by the doctor. As of today, there has been no non-invasive method for controlling the temperature dynamics in the frozen area under exposure to low temperature in real time.
Purpose. The purpose of this research is to evaluate the capabilities of thermography for the quantitative assessment of the severity of soft tissue wound in the case of thermal and other injuries, the non-invasive control of
the state of the wound during treatment, the current control of the thermal field dynamics in the frozen area of the skin exposed to low temperature effect.
Material and Methods. Eighty patients with soft tissue lesions have been surveyed with the use of an original matrix thermal imager during the treatment. The soft tissues of 30 experimental animals exposed to low temperature has been controlled with the other original thermal imager designed to measure low-temperature thermal fields.
Results. A prognostic method for assessing the category of healing potential of burn wound based on the average relative temperature has been proposed. The ROC analysis (Receiver Operating Characteristic) has been used to assess the prognostic quality of the method: the numerical value of the area under the sensitivity and specificity curve of the method is 0.79, which corresponds to a good quality of the prognostic method. It has been found that the ratio of primary necrosis area diameter to that of frozen area is 0.63 ± 0.3, at the used parameters of low-temperature impact. During the thawing, a long quasi-stable stage of the sizes and temperatures of the frozen area has been observed.
Conclusions. The thermography method has been established to be successfully used both for the monitoring of soft tissue lesions at all treatment stages, including the quantitative assessment of the healing potential of burn wounds and for the intraoperative control of the frozen area parameters during tissue cryo-destruction.
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