Radiation Technology for the Manufacture of Medical Products with Nanosilver: from Development to Commercialization
Keywords:innovation, medical, technology, development, roadmap of commercialization
Introduction. The distance between the obtainment of a researchresult and the appearance on the market of a new product is large in the sense of time and efforts and has certain specific features, depending on industry.
Problem Statement. The search and implementation of advanced materials,in particular in the field of radiation technology for the manufacture of medical products from metal-water-polymer nanocomposite is an urgent task today.
Purpose. The purpose of this research is the popularization of the technology for the manufacture of medical products from metal-water-polymer nanocomposite and the dissemination of experience in bringing R&D product to commercialization.
Material and Methods. High molecular weight polymers, silver salts, and water have been used. The electron irradiation method, optical spectroscopy, electron microscopy, microbiological analysis, and the method for curing thermal injuries and purulent wounds.
Results. The regularities of the effect of radiation on the microstructure and properties of hydrogels based on the polyvinyl alcohol — polyethylene glycol system and on the formation and stability of silver nanoparticles in the composition of 3D polymer networkshave been established. A technology for manufacturing a metal-waterpolymer nanocomposite with nanosilver has been developed; the bactericidal properties of the nanocomposite have been experimentally demonstrated. The technology formanufacturingmedical products from this nanocomposite under the HYDROBINT trademark has been developed and put into production. The organizational and technical procedures for the state certification of HYDROBINT medical products, asestablished by the legislation of Ukraine, have been described. The medical results of their use have been illustrated. A road map of developer’sactions for commercialization of innovation product has been proposed.
Conclusions. Electronic irradiation of polymer hydrogels makes it possible to create new composite materials with properties relevant for the treatment of wounds and inflammations. The products made of such composites are effective in medical practice and commercially attractive in the market. Practical recommendations for the commercialization of an R & D innovation in the form of a roadmap for the developer’s actions have been offered.
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